2022 Student Research Conference:
35th Annual Student Research Conference

Program

Program-At-A-Glance

 • https://flipgrid.com/d54e4a1e
SESSION v-3
Asynchronous Virtual -
Science & Mathematics

v-3 - 3

BROOKE L. DIEHL* and ALICIA A. KOOGLER
Dr. Daniela Ostrowski and Dr. Tim Ostrowski (A.T Still University), Faculty Mentors

Oxidative Stress in an Alzheimer’s Disease-Induced Rat Model

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v-3 - 4

SAMANTHA A. WEBSTER
Dr. Cassidy Dobson, Faculty Mentor

Optimizing the Aggregation of Gamma S Crystallin

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v-3 - 6

SUTTON Q. PURINTON
Dr. Cassidy Dobson, Faculty Mentor

Determination of the Impact of Copper(II) chloride on DBF as a Molecular Chaperone for Gamma Crystallin D

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v-3 - 7

COLLIN J. HANSEN
Dr. Bill Miller, Faculty Mentor

Computational investigation of the PD1/PDL2 allosteric binding site

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v-3 - 8

CHANZ S. SILKEY
Dr. Bill Miller, Faculty Mentor

Computational Investigation of Potential Small Molecule Inhibitors of Zika Virus's NS2B-NS3 Protease

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v-3 - 9

GRANT M. FREITAS
Dr. Bill Miller, Faculty Mentor

Inhibiting SARS-CoV-2: A Computational Approach

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v-3 - 11

CORBIN A. ESTES
Dr. Cassidy Dobson, Faculty Mentor

Investigation into Higher Ratios of DBF Compared to Denatured Lysozyme to Determine the Chaperone Activity of DBF

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v-3 - 12

KALLISTA M. STUBBLEFIELD
Dr. Joanna Hubbard, Faculty Mentor

Does Mercury Exposure in an Insectivorous Bird Affect Development of a Sexually Selected Trait?

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8:30-10:00 • MG 2001
SESSION 105
Oral Presentation- 105 -
Biochemistry & Molecular Biology I

Presiding: Dr. Cassidy Dobson

8:30

105 - 1  JONATHAN C. BRADFIELD
Dr. Bill Miller, Faculty Mentor

Computational Investigation of the Aducanumab Antibody in its Binding to Amyloid-β Species Associated with Alzheimer’s Disease

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8:45

105 - 2  KATHLEEN G. LOVE* and FARIDA A. ELKADI
Dr. Brittany Hagenhoff , Faculty Mentor

Potential of Polyphenols in the Prevention of Alzheimer's Disease

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9:00

105 - 3  DOMINIC A. CAPUTA
Dr. Bill Miller, Faculty Mentor

Computational Drug Discovery of APOBEC3B Inhibitors as a Treatment for Epithelial Cancers

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9:15

105 - 4  LIZZIE CREMER
Dr. Bill Miller, Faculty Mentor

Computational Drug Design to Inhibit the Zika NS2B/NS3 Protease

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9:30

105 - 5  GUTHRIE L. STROH
Dr. Cassidy Dobson, Faculty Mentor

Investigation into the Efficacy of Urea-Spiked Lysozyme Assays to Demonstrate the Chaperone Activity of DBF Enzyme on Protein Aggregates

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9:45

105 - 6  CHRISTINE W. CHEN
Dr. Bill Miller, Faculty Mentor

Computational Investigation of Stilbenoids as Aggregation Inhibitors of Amyloid β as it Relates to Alzheimer’s Disease

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8:30-10:00 • MG 1000
SESSION 106
Oral Presentation- 106 -
Biology

Presiding: Dr. Brett Berke

8:30

106 - 1  LEAH M. CHANEY
Dr. Cassidy Dobson, Faculty Mentor

Mutagenesis of Disulfide Bond Forming Enzyme

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8:45

106 - 2  MANIE BREMA
Dr. Stephanie L. Maiden, Faculty Mentor

The Role of MRP-5 Exporting Heme to the Hypodermis In Adult Caenorhabditis elegans 

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10:15-11:45 • MG 2001
SESSION 205
Oral Presentation- 205 -
Biochemistry & Molecular Biology II

Presiding: Dr. Bill Miller III

10:15

205 - 1  CADE K. ROHLER
Dr. Cassidy Dobson, Faculty Mentor

Chaperoned Aggregation of Gamma D Crystallin Proteins

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10:30

205 - 2  DIANA E. HECKERT
Dr. Bill Miller, Faculty Mentor

Determining Selectivity of PahZ1KT-1 in Polyaspartic Acid Hydrolysis

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10:45

205 - 3  JACKSON DYROFF
Dr. Bill Miller, Faculty Mentor

Molecular Dynamics Investigation of Amyloid β Polyphenol Inhibitors in Alzheimer’s Disease

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11:00

205 - 4  ALISON REGINA
Dr. Cassidy Dobson, Faculty Mentor

Determination of the Ratio of Oxidized Cysteine to G-S

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11:15

205 - 5  GEORGIA R. HOLLINGSWORTH
Dr. Bill Miller, Faculty Mentor

Early Design of Aromatase Inhibitors as a Treatment for Endometriosis using Computational Methods

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11:30

205 - 6  HANNAH C. ZIMMERMAN
Dr. Bill Miller, Faculty Mentor

Investigation of Stilbenoids on the Disaggregation of the Amyloid β Protein for Alzheimer’s Disease

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12:00 - 1:00 pm • MG 2001 & Zoom
Plenary Address- Dr. Sonia Arteaga

Environmental influences on Child Health Outcomes (ECHO) Program

The plenary speaker will be joining via Zoom. Come to MG 2001 for a live showing or join via Zoom- https://truman-edu.zoom.us/j/98415632910


1:15-2:45 • MG 2001
SESSION 305
Oral Presentation- 305 -
Biochemistry & Molecular Biology III

Presiding: Dr. Cassidy Dobson

1:15

305 - 1  ALEXANDRA P. PLATT
Dr. Bill Miller, Faculty Mentor

Computational Investigation of Polyphenols as Inhibitors to the Aggregation of Amyloid β in Alzheimer’s Disease

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1:30

305 - 2  MARGO C. MOTES* and RACHEL A. STANFIELD
Dr. Tim Humphry, Faculty Mentor

Synthesis of 5-methyl-5-sulfato-4-hydroxy-furanone

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1:45

305 - 3  ADAM D. VASKE* and ELLA MOZIER
Dr. Brittany Hagenhoff , Faculty Mentor

Using Analytical Methods to Determine Polyphenol Effect on Aβ Aggregation

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2:00

305 - 4  KARISSA P. WILLIAMS
Dr. Cassidy Dobson, Faculty Mentor

Using Disulfide Bond Forming Enzyme to Prevent Gamma-D Crystallin Aggregation

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2:15

305 - 5  RICHARD W. PARKS
Dr. Bill Miller, Faculty Mentor

Computational Chemistry Exploration of Inhibitors for APOBEC3B as a Potential Cancer Treatment

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2:30

305 - 6  SARAH E. HOLMES
Dr. Bill Miller, Faculty Mentor

Computational Drug Design of Aromatase Inhibitors as a Treatment for Endometriosis

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3:00-4:00 • SUB Activities Room
SESSION P-2
Poster -
Science & Mathematics

P-2 - 6

MEGHAN C. NOVOTNY* and AUDREY HEATHCOTE
Dr. Yohei Norimatsu (A.T. Still University ) and Dr. Stephen Hudman, Faculty Mentors

Expression of KCNJ5 with KCNJ3 and OPRM1 in Xenopus Oocytes

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P-2 - 11

ISAAC J. VILCHIS
Dr. Joyce Patrick, Faculty Mentor

Motility of Soil Bacteria Bacillus subtilis In Vitro

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P-2 - 12

MORGAN D. PAYNE*, HUNTER J. MADISON, SARAH G. SIMONS, EZRA G. ORTBALS, and MAR AGELET
Dr. Brett A. Berke, Faculty Mentor

Understanding motoneuron cell death in ALS using the fruit fly Drosophila melanogaster

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P-2 - 13

CHARAN DYAVANAPALLI
Dr. Daniela Ostrowski and Dr. Tim Ostrowski (A.T Still University), Faculty Mentors

Comparison of vGLUT2 expression in Control and Alzheimer’s Disease-induced rats

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P-2 - 14

ALICIA A. KOOGLER
Dr. Daniela Ostrowski and Dr. Tim Ostrowski (A.T Still University), Faculty Mentors

Alteration of the glutamate signaling in the nucleus tractus solitarii of Alzheimer’s disease-induced rats

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P-2 - 15

BROOKE L. DIEHL
Dr. Daniela Ostrowski and Dr. Tim Ostrowski (A.T Still University), Faculty Mentors

Alterations of the Glutamate Signaling in the Hippocampus of Alzheimer’s Disease-Induced Rats

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P-2 - 16

CASSADI FORMAN
Dr. Daniela Ostrowski and Dr. Tim Ostrowski (A.T Still University), Faculty Mentors

Quantification of Beta-1-Adrenergic Receptors in Hearts of Alzheimer’s Induced Rats Using Western Blot Technique

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P-2 - 17

KEIRA SPROGOE
Dr. Daniela Ostrowski, Faculty Mentor

Reduction of Methanol-Containing Hazardous Waste Produced By the Western Blot Method

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P-2 - 18

ELIZABETH J. THOMPSON
Dr. Stephen Hudman and Dr. Yohei Norimatsu (A.T. Still University ), Faculty Mentors

Investigating the True Open Structure of the CFTR Protein Using Site-Directed PCR Mutagenesis

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P-2 - 19

PEYTON G. WILLIAMS* and AINSLEY P. LAMORE
Dr. Bill Miller, Faculty Mentor

Novel Inhibitors of HIV Viral Infectivity Factor using Computational Design and Analysis

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P-2 - 20

ANNA E. BURNS* and CHRISTINA M. JUROTICH
Dr. Yohei Norimatsu (ATSU Department of Physiology) and Dr. Stephen Hudman, Faculty Mentors

Analyzing the effects of the potassium channel KCNJ6 on the mu Opioid Receptor

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P-2 - 21

JAKE A. COLLINS
Dr. Bill Miller, Faculty Mentor

Characterization of Sphingomonas sp. KT-1 PahZ1 Interface Mutant Domain via Crystallization and QM/MM

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P-2 - 22

THOMAS J. SCHODL
Dr. Cassidy Dobson, Faculty Mentor

Analysis of gamma-D Crystallin Aggregation in the Presence of Disulfide Bond-Forming Enzyme

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P-2 - 23

AMI R. PATEL* and HANNAH F. SANDERS
Dr. Yohei Norimatsu (A.T. Still University ) and Dr. Stephen Hudman, Faculty Mentors

Effect of Zinc on Beta2-adrenergic Receptor Signal Transduction in Xenopus Oocytes

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