Distribution of Human Papillomavirus Types in Zambia
Paula J. Richards
Dr. Michael Lockhart and Dr. Peter C. Angeletti (University of Nebraska-Lincoln), Faculty Mentors
Human Papillomaviruses (HPV) are double-stranded DNA viruses that are the cause of genital warts and are associated with 95% of cervical cancer worldwide. This was a preliminary two part study: to determine the approximate rate of infection and the types of HPV present in the Zambian population and to determine if Human Immunodeficiency Virus (HIV) increases the incidence of HPV detection. Polymerase chain reaction (PCR) using two different primers (CpI/II and GP5+/6+) was used to test for the presence of HPV DNA. The most common type of HPV DNA found was type 16 (35%). Only one sample tested was positive for only a low risk type (type 6). This preliminary study showed a higher rate of HPV DNA detection in HIV positive samples.
Keywords: Human Papillomavirus, Polymerase chain rea
Topic(s):Biology
Presentation Type: Poster
Session: 29-70
Location: OP Lobby & Atrium
Time: 1:15