2026 Student Research Conference:
39th Annual Student Research Conference

How Protective is Your Toothpaste? An Ion-Selective Electrode Approach to Determining Fluoride Content in Toothpaste


Sofia Kattentidt*, Ashelynn Courtney, Alex Kepes, and Laura Varo
Dr. Barbara Kramer, Faculty Mentor

Fluoride is a key ingredient in toothpaste, contributing to enamel remineralization and the prevention of dental cavities. This study aims to quantify fluoride concentrations in three commercially available and marketed as “protective” toothpastes: Sensodyne Repair and Protect, Crest Plus Cavity Protection, and Colgate Total Active Protection. Fluoride ion-selective electrode (ISE) analysis will be used to measure aqueous free fluoride, while spiked blanks and samples will evaluate method accuracy. Calibration curves generated from the fluoride standards will allow conversion of electrode potentials to fluoride concentration. The results will help assess the consistency of labeled fluoride content across brands and answer the question of whether these toothpastes are actually protective, based on the amount of fluoride found.

Keywords: Chemistry, Ion-Selective Electrode, ISE, Fluoride, Toothpaste

Topic(s):Chemistry

Presentation Type: Poster Presentation

Session: TBA
Location: TBA
Time: TBA

* Indicates the Student Presenter
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