X-Ray Diffraction Studies of Potential Anti-Viral Compounds, Triruthenium Complexes, and a Series of Ethylenediammonium Salts
Laura M. Tvedte
Dr. Russell G. Baughman, Faculty Mentor
X-ray diffraction has been used to study potential anti-viral compounds, a common ligand, and triruthenium complexes. X-ray diffraction allows for determination of crystal and molecular structures at a high level of precision. Thiazolone-based sulfonamides have shown promise as inhibitiors of the Hepatitis C virus (HCV), and their study using X-ray diffraction allows for better understanding of the synthesis method used. The common use of ethylenediamine in inorganic chemistry makes this ligand an interesting molecule to study. The molecule is being studied as its ethylenediammonium salts (bromide, iodide, chloride) to examine the contributions of the various halides on the structure of their respective salts. Triruthenium complexes synthesized by a collaborator have had their structures determined and the structures are in preparation for publication. The current lack of study of these topics in the literature allows for a wide array of potential further studies.
Keywords: X-Ray Diffraction, Anti-Viral Compounds, Inorganic Chemistry, Ruthenium Chemistry, Hepatitis C Virus, Molecular Structure, Ethylenediammonium Salts
Topic(s):Chemistry
Presentation Type: Oral Paper
Session: 43-4
Location: MG 1000
Time: 3:30