2021 Student Research Conference:
34th Annual Student Research Conference

Program

Program-At-A-Glance

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SESSION V-3
Asynchronous Virtual -
Biochemistry & Molecular Biology

Presiding:

0:00

V-3 - 1  MARISSA D. PINA
Dr. Bill R. Miller, Faculty Mentor

Computational Drug Discovery for a Protease Inhibitor as a Treatment for the Coronavirus Disease

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0:00

V-3 - 2  ALEXANDRA M. MARKO
Dr. Cassidy Dobson, Faculty Mentor

Gamma Crystallin Aggregation in the Presence of Disulfide Bond Forming (DBF) Enzyme

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0:00

V-3 - 3  ADDISON M. LEABO
Dr. Cassidy Dobson, Faculty Mentor

Aggregation of Gamma Crystallin Proteins

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0:00

V-3 - 4  DEREK M. EMPSON
Dr. Cassidy Dobson, Faculty Mentor

The Effect of Two Subsequent Purifications on DBF Using Immobilized Metal Affinity Column Chromatography

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0:00

V-3 - 5  COLLIN J. HANSEN
Dr. Bill R. Miller, Faculty Mentor

Novel drug design to inhibit the ZIKV NS2B-NS3 protease

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0:00

V-3 - 6  CORBIN A. ESTES
Dr. Cassidy Dobson, Faculty Mentor

Expression and Purification of DBF

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0:00

V-3 - 7  AVERY T. EVANS
Dr. Bill R. Miller, Faculty Mentor

Investigation Into Potential Inhibitors for Alpha-Synuclein

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0:00

V-3 - 8  BROCK BOYSAN
Dr. Bill R. Miller, Faculty Mentor

Computational Investigation of Potential Inhibitors for HIV Viral Infectivity Factor

 

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0:00

V-3 - 9  JACKSON DYROFF
Dr. Bill R. Miller, Faculty Mentor

Molecular Dynamics Investigation of Amyloid β Polyphenol Inhibitors in Alzheimer’s Disease

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0:00

V-3 - 10  ALEXANDRA P. PLATT
Dr. Bill R. Miller, Faculty Mentor

Computational Investigation of Polyphenols as Inhibitors to the Aggregation of Amyloid β in Alzheimer’s Disease

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0:00

V-3 - 11  ELIZABETH E. CREMER
Dr. Bill R. Miller, Faculty Mentor

Computational Drug Design to Inhibit the Zika NS2B/NS3 Protease

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0:00

V-3 - 12  SAUL ARMENDARIZ LOBERA
Dr. Bill R. Miller, Faculty Mentor

Inhibition of DNA Deaminase APOBEC3B Using Computational Methods

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0:00

V-3 - 13  GUTHRIE L. STROH
Dr. Cassidy Dobson, Faculty Mentor

Qualitative Study of the Chaperone Activity of DBF Enzyme on Protein Aggregates

 

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0:00

V-3 - 14  JAKE A. COLLINS
Dr. Bill R. Miller, Faculty Mentor

Investigating Deprotonation of DNA Base Pairs by DNA Polymerase I in G. stearothermophilus Using QM/MM

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0:00

V-3 - 15  REUBEN KERN
Dr. Cassidy Dobson, Faculty Mentor

Mutagenesis of Disulfide Bond Forming Enzyme

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0:00

V-3 - 16  JONATHAN C. BRADFIELD
Dr. Bill R. Miller, Faculty Mentor

Computational Investigation of the Role of Polyphenol Drugs in the Disaggregation of Amyloid-Beta Plaques Associated with Alzheimer's Disease

 

 

 

 

 

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0:00

V-3 - 17  ALLISON B. ESSELMAN
Dr. Bill R. Miller, Faculty Mentor

Optimization of Bisintercalator Drug Modifications as a Treatment for Breast Cancer Utilizing Common Structural Drug Design Techniques and Molecular Dynamics

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0:00

V-3 - 18  CADE K. ROHLER
Dr. Cassidy Dobson, Faculty Mentor

Optimization of the Aggregation of Gamma D Crystallin Protein

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0:00

V-3 - 19  MARGO C. MOTES
Dr. Tim Humphry, Faculty Mentor

Synthesis of 1,1-methyl-sulfate-2-gamma-lactone-ol

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0:00

V-3 - 20  MOLLY M. HUEBNER
Dr. Bill R. Miller, Faculty Mentor

Computational Drug Discovery of APOBEC3B Inhibitors as a Treatment for Epithelial Cancers

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0:00

V-3 - 21  MADISON E. WALKER
Dr. Bill R. Miller, Faculty Mentor

Modeling the Inhibition of Flavonoid Derivatives on Aromatase Using Molecular Dynamics

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0:00

V-3 - 22  MAHAN J. HADJIAN
Dr. Brittany Hagenhoff , Faculty Mentor

IN VITRO EFFECTS OF SALINITY AND NORDIHYDROGUAIARETIC ACID ON Aβ 1-28 AGGREGATION

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0:00

V-3 - 23  RICHARD W. PARKS
Dr. Bill R. Miller, Faculty Mentor

Computational Chemistry Exploration of Inhibitors for APOBEC3B as a Potential Cancer Treatment

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SESSION V-4
Asynchronous Virtual -
Biology

Presiding:

0:00

V-4 - 3  KATHLEEN S. MCNEARY
Dr. Diane Janick-Buckner, Faculty Mentor
Investigation of Root Zone Phytoene Synthase (PSY) and Alfin (ALF) Gene Expression in Salt Stressed Zea mays Inbred Lines Mo17 & B73

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8:30-10:00 • SUB Activities Room
SESSION 102
Face-to-Face Oral Presentation- 102 -

Presiding: Dr. Bill Miller

8:30

102 - 1  ROBERT D. CAMPBELL
Dr. Bill R. Miller, Faculty Mentor

Computational Drug Design for Novel Inhibitors of the Zika NS2B-NS3 Protease

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10:30-11:30 • SUB Activities Room
SESSION 202
Face-to-Face Oral Presentation- 202 -

Presiding: Dr. Brandy Schneider

11:00

202 - 3  GRANT M. FREITAS
Dr. Bill R. Miller, Faculty Mentor

Inhibiting SARS-CoV-2: A Computational Approach

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12:00 - 1:00 pm • Zoom- https://zoom.us/j/93884072639
Plenary Session- Dr. Kalynda C. Smith

The Exploration of Identity Intersectionality of Black Female STEM Undergraduates

This study examined the intersectionality of racial, gender, and academic identity of Black female STEM undergraduates attending a historically black college and university (HBCU). Research has demonstrated that the intersection of race and gender are likely to subject Black women to prejudice and ostracism in STEM disciplines. Data revealed that Black women experienced racial and gender intersectionality, but that quantitative findings demonstrated a decrease in Black racial centrality and private regard over time. Qualitative reports suggested otherwise. Further research must be done to understand the differences between the quantitative and qualitative findings. Dr. Kalynda C. Smith is currently an Assistant Professor of Psychology at North Carolina A&T State University. Her current teaching load is primarily social psychology and cultural psychology courses. She is also a Co-PI of several STEM education NSF-funded projects focused on the academic achievement of students of color, especially as it pertains to pursuing research and graduate training. These interdisciplinary projects include faculty from education, engineering, mathematics, political science, social work and sociology and are cross-institutional. Her duties include quantitative and qualitative data collection, analyses, interpretation, and publication. Dr. Smith is primarily interested in how identity impacts the achievement outcomes of students of color, including, but not limited to racial identity, gender identity and academic identity.


1:30-3:00 • SUB GEO
SESSION 301
Face-to-Face Oral Presentation- 301 -

Presiding: Dr. Cassidy Dobson

1:30

301 - 1  RYAN P. POLAND
Dr. Cassidy Dobson, Faculty Mentor

Determination of Re-Folding Effectiveness of DBF Through Lysozyme Activity Assays

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3:30-5:00 • SUB GEO
SESSION 401
Face-to-Face Oral Presentation- 401 -

Presiding: Dr. Tim Wiser

3:30

401 - 1  KERSTIN E. PETERSON
Dr. Cassidy Dobson, Faculty Mentor

Disulfide Bond Forming Enzyme Activity via Lysozyme Assay

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4:15

401 - 4  VALERIE S. WINKLER
Dr. Brittany Hagenhoff , Faculty Mentor

The Effect of Curcumin on the Fibril Formation of Amyloid-β Fragments 1-16, 1-28, and 1-40

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